The Reproductive System
Azoospermia
Man Woman
The sexual and reproductive organs on the outside of a woman’s body are called the external genitals. There are three openings in the genital area. In front is the urethra, from where urine comes out; below the urethra is the opening to the vagina which is called the introit-us; and the third is the anus from where a bowel movement leaves the body.
The outer genital area is called the vulva. The vulva includes the clitoris, the labia majors and the labia minors. The most sensitive part of the genital area is the clitoris. This is a pea-shaped organ which is full of nerve endings and its only purpose is to provide sexual pleasure. The clitoris is protected by hood of skin, and is the equivalent of the male penis.
The labia majora or outer lips surround the opening to the vagina. They are made of fatty tissue that cushions and protects the vaginal opening between these outer lips are labia minora or inner lips these lips are sensitive to sexual stimuli. As they get stimulated, they take on a deeper colour and begin to swell.
The vagina is a muscular tunnel that connects the uterus (or womb) to the outside of the body. The vagina provides an exit for the menstrual fluid, and an entrance for the male’s semen, which is ejaculated during sexual intercourse. Normally flat, like a collapsed balloon, the vagina is extremely flexible and can stretch to accommodate a tampon, a penis or even a baby’s head (during childbirth)! The walls of the vagina are muscular, smooth and soft. The vagina is a closed space, which ends at the cervix.
The uterus or the wombs, is the palace where the fertilized eggs grows and develops into a baby during pregnancy. The uterus lies deep in the lower abdomen the pelvis-and is just behind the urinary bladder. The uterus is a hollow organ shaped like a pear end is about the size of the fist. Inside the muscular walls of the uterus is a very rich lining, namely the endometrium, and it is in this lining that the fertilized egg gets implanted. If, however, pregnancy does not occur, this lining is shed along with blood in the form of the menstrual flow.
The neck of the uterus is called the cervix. It connects the uterus to the vagina and contains special glands called crypts that produce mucus, which helps to keep bacteria out of the uterus. The cervical mucus also helps sperm in entering the uterus when the egg is ripe.
Two tubes, known as fallopian tubes, are attached to the upper part of the uterus on either side and are about 10 cm long. They are about as thick as a piece of noodles each tube forms a narrow passageway that opens like a funnel into the abdominal cavity, near the ovaries funnel into the abdominal cavity, near the ovaries (described later). The ends of the fallopian tubes are draped over the two ovaries and they serve as a passage for the egg to travel from the ovary into the uterus. Each fallopian tube is lined by millions of tiny hairs called cilia that beat rhythmically to propel the egg forward. Of course, the tube is not just a pathway- it performs other functions too, including nourishing the egg and the early embryo in its cavity. Also, the sperm fertilize the egg in one of the fallopian tubes.
The two almond sized ovaries are perched in the pelvis, one on each side, just within the fallopian tubes’ grasp. Each month, at the time of ovulation, a mature egg is released by an ovary. This egg is “picked up” by the fimbria (a bordering fringe at the end of the fallopian tubes) and drawn into the fallopian tube. How does the egg reach the fallopian tube? When ovulation occurs, the mature egg is releases from the follicle in the ovary. This process of follicular rupture looks a bit like a small volcano erupting on the ovarian surface. At this time, the tubal fiimbria, like tentactes, sweep over the surface of the ovary and actually “swallow” the egg. The egg has a shell called teh zona pelluzida which looks somewhat like the ring of saturn.The shell is surrounded by a cluster of nest cells called the corona cells, which serve to narture the egg. These cells form the cumulus oophorus, which is a sticky gel that protects the egg and also helps the beating of the hair-like cilia of the fallopian tube to propel the egg towards the uterus-like, a conveyor belt. The egg must now wait in the protective confines of the fallopian tube, for a sperm to swim up and reach it.
The ovary contains about 2 million eggs during the sixth months of fetal life. From that point onwards, the number of eggs progressively decreases, till only about 300,000 egg cells are left at the time of the birth- a lifetime’s stock. During the fertile years, fewer than 500 of these eggs will be released into the fallopian tubes- once in each menstrual cycle. One of the existing eggs becomes matured for ovulation each month, and this limited supply runs out at the time of menopause. Unlike the testes in the male, which are continually, churning out billions of new sperm, the ovary never produces any new eggs.
The menstrual cycle:
The aspect of the reproductive system of which women are most aware, the menstrual period or menstrual flow which they have every month. The time from the beginning of one period to the beginning of the next one is known as the menstrual cycle. Usually menstrual cycles last about 28-35 days, though any time period from 3 to 6 weeks is considered normal. If pregnancy does not occur, the uterus must get rid of this thick lining so that it can grow a new one in the next cycle. The old lining passes out of the uterus through the vagina as the menstrual flow.
The menstrual flow thus consists of:
(1) The shed uterine lining;
(2) Blood (this comes from the blood vessels which are torn when the lining is shed); and
(3) The degenerated unfertilized egg.
If the menstrual flow is heavy, sometimes clots may be formed in it. Sometimes, the uterine lining is shed as large fragments and these fragments may sometimes look like bits of pregnancy tissue to some women, who may think they are miscarrying. The cycle of ovarian hormone production consists of two phases. In the first phase, called the follicular phase, estrogen plays dominant role. During this phase the egg matures inside the ovary in its follicle, which consists of: the egg; the surrounding cells (which nurture the egg and are called granulosa cell and theca cell); and the fluid (called follicular fluid) which accumulates in progressively larger amounts during this phase. The follicle secretes a large amount of estrogen (produced by the granulosa cells) into the bloodstream, and this estrogen circulates to the uterus, where it stimulates the endometrium to thicken.
The second phase of hormone production begins after ovulation, midway through the cycle, when the follicle changes into a small mass of yellow tissue called the corpus luteum. Traveling through the bloodstream to the uterus, progesterone complements the work begun by estrogen by stimulating the endometrium to mature and making it possible for fertilized egg to get implanted in it. In case pregnancy does not occur, the rate of production of estrogen and progesterone begins to fall 10 to 14 days after ovulation as the corpus luteum dies, and the endometrium is shed from the body during the menstrual period.
Women Man
The male reproductive system begins in the scrotum, which is the sack behind the penis. This sack contains two testicles, which manufacture a man’s sex cells, called sperm, and the male sex hormone called testosterone. The testicles feel solid, nut little spongy, like hard-boiled eggs without the shell. They hang from cord called the spermatic cord.
The testicles produce sperm best when they are at a temperature, which is a few degrees below the normal body temperature. This is why nature has designed a scrotum – so that the testes can hang outside the body to keep them cool. The testicles start producing sperm when a young man reaches puberty. This is in response to the male sex hormone, testosterone, which starts being produced at this time. The tested keep on producing sperm for the rest of the man’s life.
The sperm are producing inside several hundred coiled microscopic tubules called seminiferous tubules present in the testes. These tubules converge and collect in the form of a delta (the mouth of a river) near the upper part of the testis called the rete testis, which then empties through a series of very small ducts, called the efferent ducts, out of the testis towards the epididymis. The tail of the epididymis them leads to the vas deferens a thin cord like muscular tube, which is part of the spermatic cord and which ends at the ejaculatory duct in the prostate. In the prostate the ejaculatory duct is joined by the seminal vesicle ducts and they all open into the urethra in the penis.
Mature sperm take about 75 days to develop in a process called spermatogenesis. Sperm production takes places as though the sperm were on an assembly line, with the more mature sperm being passed along towards the center of the tubule, from where they swim towards the efferent ducts of the testis towards the epididymis. This assembly line can be very “temperamental”; things may often go wrong, leading to low sperm counts.
When the sperm leave the testis, they are not yet able to swim on their own. They acquire the capacity to do so in their passage through the epididymis, which acts like a “swimming school” for the sperm. They spend between 2 and 15 days here during which they attain maturity and fertilizing potential. During ejaculation, the muscles of the epididymis and vas deferens contract to propel the sperm into the ejaculatory duct. Here the sperm is joined by the secretions of the seminal vesicles and the prostate gland (which contribute the bulk of the seminal fluid) to form the semen. The powerful muscles surrounding the base of the urethra then cause the semen to squirt out of the penis at the time of orgasm. The remarkable aspect of this system is that semen and urine never mix in a healthy male (even though the final passage for both is common). This is because the bladder sphincter muscle contracts during sexual stimulation, thus closing the exit from the bladder to the urethra during ejaculation, thereby preventing urine from leaking forward out of he bladder during sex and also preventing semen from accidentally going backward in to the bladder.
During ejaculation about one teaspoon of semen spurts out of the penis. Semen has a milky white colour, with the consistency of egg white. Sperm account for only about 2% to 3% of semen. Most of the semen consists of seminal fluid, i.e., the secretion of the seminal vesicles and the prostate gland, which provide a vehicle for carrying the sperm into the vagina.
A normal ejaculation contains 200 to 500 million sperm. How can so many sperm fit into only a teaspoon of semen? Simple- sperm are very tiny. If one average ejaculation filled an Olympic size swimming pool, each sperm cell would still be smaller than a goldfish. Sperm are the smallest living cells in the human body and the egg the largest. Basically, sperm are designed so that they can deliver there contents-the male genetic material- to the egg. This is why sperm are designed like projectiles- to male DNA is found in the chromosomes in the sperm head nucleus, and the tail propels the sperm up towards the egg.
Sperm are very fragile. Consequently, very few are able to survive the hazards swim through the female reproductive system in order to reach the egg. This is why a male produces such a large number of sperm. Perhaps the reason for this is also an “evolutionary hangover”- a legacy from our past. To amplify: female fish deposit eggs on the seabed and the male fish then sprays his sperm into the sea water. The wastage of sperm in the water is tremendous, and this is why male fish need to produce millions of sperm, in order to ensure that at least some sperm reach the egg.
What happen to the sperm if you do not indulge in sex for many days? Unfortunately you can not store up sperm. If ejaculation does not occur for many days, the sperm in the reproductive ducts simply die. This is why a sperm count carried out after many days of abstinence from sex shows a high number of dead or Immotile sperm. But there is no need to be discouraged by this. The good news is that just like you cannot store your sperm, you can not run out of sperm either- masturbation and sexual intercourse cannot “use-up” sperm . The body keeps producing sperm as long as a man has even one normal testicle.
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(1) Is infertility hereditary ?
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(2) Does a retroverted (”tipped”) uterus causes infertility because the semen can not swim into the cervix?
ANS- About one in five women will have a retroverted uterus. If the uterus is freely mobile, this is normal and is not causes of infertility. Such a condition is not an indication for surgery.
(3) Does stress cause infertility?
ANS- There is no evidence that stress causes infertility. Remember all infertile patients are under stress, it’s not stress, which causes infertility, it’s the infertility, which causes the stress.
(4) I have never had symptoms of a pelvic infection, so I can’t have blocked tubes?
ANS- Many pelvic infections do not cause any symptoms at all, but can nevertheless cause severe damage, which is sometimes irreversible, to the fallopian tubes.
(5) “My gynecologist has carried out an internal examination and said that I am normal; therefor, I should have no problem getting pregnant”?
ANS- A routine gynecological examination does not provide information about possible problems, which can cause infertility.
(6) Should we be having intercourse everyday to have pregnancy?
ANS-Sperm remains alive and active in cervical mucus for 48-72 hours following sexual intercourse; therefore, it isn’t necessary to plan your love making on a rigid schedule. Although having sexual intercourse near the time of ovulation is important, no single day is critical. So, do not be concerned if intercourse is not possible or practical on the day of ovulation.
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